As some of u know that I am using mice for my research project. The cool thing is I am not using the normal mice that u can buy in the pet shop or the boring strains such as Bab/c or Wistar but NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ or NSG for short.
The beauty of this strain is it has no T cells, B cells nor NK cells that help to regulate immuno response towards invading cells therefore its perfect for transplantation of organs, xenografs and etc. Also it does not leak when it grows old unlike Nude Mice.
The downside is they are a bit aggressive when handle and have a weird reaction towards ether or G.A. They will sort of run around the cage avoiding it unlike other strains which are more docile when under G.A.
These white mice are so beautiful and fluffy when they mature, u will be begging to make coats out of them when u touch the fur.
Oh yeah, they are fast and consistent breeders, a simple setup set needs 2 dames and 1 sire which can be kept for 5 cycles or more. The genotype stays true for each generation.
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